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健康尼日利亚儿童的血清转钴胺素

Serum transcobalamins in healthy Nigerian children.

作者信息

Osifo B O, Parmentier Y, Gerard P, Nicolas J P

出版信息

Acta Haematol. 1982;68(4):300-6. doi: 10.1159/000206996.

DOI:10.1159/000206996
PMID:6817573
Abstract

The unsaturated vitamin B12-binding capacity (UB12BC) and the three transcobalamins (TC I, TC II, TC III) have been studied in the serum of normal healthy Nigerian children. The serum UB12BC level was very high in the children: TC I accounted for 39.5% of UB12BC, TC II accounted for 49.5% and TC III accounted for 11%. The results are discussed in the light of the variations in the distribution of transcobalamins in children from what has been previously reported among the African adults. The high percentage of TC I in the children is discussed in the light of a possible immunological role of this transcobalamin. There was an inverse relationship between TC I and TC II levels. A sex difference in UB12BC and TC I levels was observed. The girls had higher UB12BC and this was due to higher TC I, but the advantage of this is not clear.

摘要

对正常健康的尼日利亚儿童血清中的不饱和维生素B12结合能力(UB12BC)及三种转钴胺素(转钴胺素I、转钴胺素II、转钴胺素III)进行了研究。儿童血清中的UB12BC水平非常高:转钴胺素I占UB12BC的39.5%,转钴胺素II占49.5%,转钴胺素III占11%。根据之前报道的非洲成年人中转钴胺素分布情况的差异,对这些结果进行了讨论。鉴于这种转钴胺素可能具有的免疫作用,对儿童中转钴胺素I的高比例进行了讨论。转钴胺素I和转钴胺素II水平之间呈负相关。观察到UB12BC和转钴胺素I水平存在性别差异。女孩的UB12BC较高,这是由于转钴胺素I较高,但这种优势尚不清楚。

相似文献

1
Serum transcobalamins in healthy Nigerian children.健康尼日利亚儿童的血清转钴胺素
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引用本文的文献

1
Variant-specific differences in human unsaturated transcobalamin II.人不饱和转钴胺素II的变异特异性差异。
Biochem Genet. 1986 Feb;24(1-2):103-14. doi: 10.1007/BF00502982.