Hanen A, Roubaud P, Goux J M
C R Seances Acad Sci III. 1982 Sep 27;295(3):231-4.
On a theoretical model of cellular genome we demonstrate that the clonal multiplication induces an ineluctable decline of the "mitotic capacity". A cellular population is formed, the genomes of which include no more than one of each fundamental genetic element.
在细胞基因组的理论模型中，我们证明克隆增殖会导致“有丝分裂能力”不可避免地下降。形成了一个细胞群体，其基因组中每种基本遗传元件不超过一个。
