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肺癌术后辅助放疗的评估

Evaluation of adjuvant postoperative radiotherapy for lung cancer.

作者信息

Chung C K, Stryker J A, O'Neill M, DeMuth W E

出版信息

Int J Radiat Oncol Biol Phys. 1982 Nov;8(11):1877-80. doi: 10.1016/0360-3016(82)90444-8.

Abstract

One hundred eighteen patients with lung cancer were retrospectively analyzed to determine whether postoperative radiotherapy (RT) improves survival. Patterns of treatment failure and three year NED (no evidence of disease) survival rates were assessed according to extent of tumor spread, histology, and treatment method. Patients with hilar or mediastinal node metastases were at higher risk of local failure compared to those with negative nodes. Postoperative RT reduced local recurrence and improved 3 year survival among patients with positive nodes. However, postoperative RT did not improve survival among those with negative nodes. Our data indicated that patients with positive hilar or mediastinal nodes may require postoperative RT to improve survival.

摘要

对118例肺癌患者进行回顾性分析,以确定术后放疗(RT)是否能提高生存率。根据肿瘤扩散程度、组织学和治疗方法评估治疗失败模式和三年无疾病证据(NED)生存率。与无淋巴结转移的患者相比,有肺门或纵隔淋巴结转移的患者发生局部失败的风险更高。术后放疗降低了阳性淋巴结患者的局部复发率并提高了三年生存率。然而,术后放疗并未提高阴性淋巴结患者的生存率。我们的数据表明,有阳性肺门或纵隔淋巴结的患者可能需要术后放疗以提高生存率。

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