de Reviers M, Hochereau-de Reviers M T, Blanc M R, Brillard J P, Courot M, Pelletier J
Reprod Nutr Dev (1980). 1980;20(1B):241-9. doi: 10.1051/rnd:19800206.
Sertoli cells are involved in the control of spermatogenesis. In adult animals, the Sertoli cell stocks, fixed before puberty, are highly correlated with those of the germ cells. Some factors influencing Sertoli cell stock formation have been analyzed: 1) Early hemicastration of impuberal animals showed that the proliferative activities of the Sertoli and the germ cells before puberty, rather than their initial numbers at birth, were the limiting factors of their final number in adult testis. 2) During testicular growth, LH and FSH levels were correlated to Sertoli cell stocks and to germ cell production. 3) The season of birth influenced the Sertoli cell stock formation in the ram. Daylength modified testicular development in the cockerel and the sheep. 4) Between-strain differences were more marked for the testis than for body growth in the cockerel. In the ram, Sertoli cell stocks were similar between half-brothers but significantly different between sires.
支持细胞参与精子发生的调控。在成年动物中,青春期前固定的支持细胞数量与生殖细胞数量高度相关。已分析了一些影响支持细胞数量形成的因素:1)青春期前动物早期半阉割表明,青春期前支持细胞和生殖细胞的增殖活性而非出生时的初始数量是成年睾丸中它们最终数量的限制因素。2)在睾丸生长过程中,促黄体生成素(LH)和促卵泡生成素(FSH)水平与支持细胞数量及生殖细胞产生相关。3)出生季节影响公羊支持细胞数量的形成。光照时长改变公鸡和绵羊的睾丸发育。4)在公鸡中,品系间睾丸差异比身体生长差异更明显。在公羊中,半同胞间支持细胞数量相似,但不同父本间差异显著。