一种用于生长调节素的快速简易生物测定法。

A rapid simplified bioassay for somatomedin.

作者信息

Spencer G S, Taylor A M

出版信息

J Endocrinol. 1978 Jul;78(1):83-8. doi: 10.1677/joe.0.0780083.

DOI:10.1677/joe.0.0780083

Abstract

A simplified, more rapid bioassay for the estimation of somatomedin activity, based on the porcine costal cartilage bioassay, is described. A micro-scale system based on the porcine costal cartilage assay is also described. These assay systems showed no decrease in sensitivity or precision, compared with other methods, as a result of the modifications. The assays have been used for routine hospital laboratory determinations, for the estimation of somatomedin activity in normal adolescent children of both sexes and in clinical studies of scoliotic, acromegalic and hypopituitary patients.

摘要

本文描述了一种基于猪肋软骨生物测定法的简化、更快速的生长调节素活性评估生物测定法。还介绍了一种基于猪肋软骨测定法的微量系统。与其他方法相比，这些测定系统经改进后在灵敏度或精密度方面并未降低。这些测定法已用于医院实验室的常规检测，用于评估正常青春期男女儿童的生长调节素活性，以及用于脊柱侧凸、肢端肥大症和垂体功能减退患者的临床研究。