Abdelmoumene N, Maoui R, El Okby A, Benmiloud M
Ann Endocrinol (Paris). 1982 May-Jun;43(3):193-202.
Thyroid function was evaluated after thyroidectomy in 30 cases of Graves' disease. 15 patients were euthyroid, 6 of them were TRH non responsive suggesting a risk of relapse. Indeed, the 3 proven cases of relapse were TRH non responsive before relapse and remained so after treatment. The severe iodine deficiency in Algeria did not seem to increase the frequency of post-operative hypothyroidism. Neither did the duration of carbimazole therapy, the severity of thyroid lymphocytic infiltration or thyroid antibodies titer. Thyroid remnant size, although difficult to estimate, appears to be inversely related to post-operative TSH values.
对30例格雷夫斯病患者甲状腺切除术后的甲状腺功能进行了评估。15例患者甲状腺功能正常,其中6例对促甲状腺激素释放激素(TRH)无反应,提示有复发风险。实际上,3例复发确诊病例在复发前对TRH无反应,治疗后仍如此。阿尔及利亚严重的碘缺乏似乎并未增加术后甲状腺功能减退的发生率。甲巯咪唑治疗时间、甲状腺淋巴细胞浸润的严重程度或甲状腺抗体滴度也未增加其发生率。甲状腺残余大小虽然难以估计,但似乎与术后促甲状腺激素(TSH)值呈负相关。