Padeletti L, Michelucci A, Fradella G A, Brat A, Fantini F
Arch Mal Coeur Vaiss. 1982 Nov;75(11):1233-9.
A method of recording the sinus node potential (SNP) has recently been introduced in clinical electrophysiology. The sinoatrial conduction time can now be measured directly (SACTD) as the interval between the onset of the SNP and the onset of atrial activation. We measured the SACTD in 16 normal subjects and in 7 patients with sinus node dysfunction. These values were compared with those obtained by the indirect methods of Strauss et al (SACTS) and Narula et al (SACTN). In normal subjects the SACTD ranged from 50 to 130 ms (average 84,4 +/- 22,35); the SACTS, from 55 to 160 ms (92,9 +/- 29,3), and the SACTN from 70 to 175 ms (113,2 +/- 28,8). In patients with sinus node dysfunction the SACTD ranged from 200 to 290 ms (227 +/- 32,5), the SACTS, from 52 to 198 ms (111,8 +/- 59,3) and the SACTN from 89 to 251 ms (142,3 +/- 63). No significant difference was observed between normal and pathological subjects using the indirect methods of evaluation. However, the SACTD method showed a very significant difference between the two groups (p less than 0,0005) with no overlap. No correlations were observed between the values obtained by the indirect and direct methods of measuring SACT.
临床电生理学最近引入了一种记录窦房结电位(SNP)的方法。现在可以直接测量窦房传导时间(SACTD),即SNP起始与心房激动起始之间的间期。我们对16名正常受试者和7名窦房结功能障碍患者测量了SACTD。将这些值与通过Strauss等人的间接方法(SACTS)和Narula等人的间接方法(SACTN)获得的值进行比较。正常受试者的SACTD范围为50至130毫秒(平均84.4±22.35);SACTS为55至160毫秒(92.9±29.3),SACTN为70至175毫秒(113.2±28.8)。窦房结功能障碍患者的SACTD范围为200至290毫秒(227±32.5),SACTS为52至198毫秒(111.8±59.3),SACTN为89至251毫秒(142.3±63)。使用间接评估方法,正常受试者与病理受试者之间未观察到显著差异。然而,SACTD方法显示两组之间存在非常显著的差异(p<0.0005),且无重叠。测量SACT的间接方法和直接方法所获得的值之间未观察到相关性。