Viegas O A, Scott P H, Cole T J, Mansfield H N, Wharton P, Wharton B A
Br Med J (Clin Res Ed). 1982;285(6342):589-92. doi: 10.1136/bmj.285.6342.589.
At Sorrento Maternity Hospital Asian mothers whose babies had grown poorly in utero had anthropometric and biochemical evidence suggesting an inadequate nutritional state. To test this hypothesis further the effect of unselective dietary protein energy supplementation was studied. A total of 153 Asian mothers received one of three supplements from the 18th to 38th weeks of pregnancy: (a) vitamins only--vitamin C 30 mg daily, iron 3 mg daily; (b) energy--42-80 MJ; (10 000-19 000 kcal)/trimester, all from carbohydrate, plus vitamins; (c) protein energy--energy and vitamins as before, but with 5-11% of energy from milk protein. By the 28th week mothers receiving the protein energy supplement had put on more weight and more fat than the vitamin-only group. Neither protein energy nor energy supplementation alone enhanced intrauterine growth. It is concluded that dietary supplementation of all pregnant mothers does not enhance intrauterine growth.
在索伦托妇产医院,那些子宫内胎儿生长发育不良的亚洲母亲,有人体测量和生化证据表明其营养状况不佳。为了进一步验证这一假设,研究了非选择性膳食蛋白质能量补充的效果。共有153名亚洲母亲在怀孕第18周至38周期间接受了三种补充剂中的一种:(a)仅补充维生素——每日维生素C 30毫克,铁3毫克;(b)补充能量——每孕期42 - 80兆焦耳(10000 - 19000千卡),全部来自碳水化合物,外加维生素;(c)补充蛋白质能量——能量和维生素与之前相同,但能量的5 - 11%来自乳蛋白。到第28周时,接受蛋白质能量补充剂的母亲比仅补充维生素的组体重增加更多,脂肪增加更多。单独补充蛋白质能量或能量都不能促进子宫内生长。结论是,对所有孕妇进行膳食补充并不能促进子宫内生长。