癫痫患者中苯妥英钠与苯乙妥因的比较：一项双盲交叉试验。
A comparison of phenytoin and pheneturide in patients with epilepsy: a double-blind cross-over trial.
作者信息
Gibberd F B, Park D M, Scott G, Gawel M J, Fry D E, Page N G, Engler C, English J R, Rose F C
出版信息
J Neurol Neurosurg Psychiatry. 1982 Dec;45(12):1113-8. doi: 10.1136/jnnp.45.12.1113.
Abstract
A double-blind cross-over trial between pheneturide and phenytoin in ninety-four outpatients with epilepsy is described. There was no significant difference between the frequency of seizures in the two groups. The difficulties in comparing two anticonvulsants of similar efficacy are discussed particularly in relation to ethical problems, the selection of patients and trial design.
摘要
本文描述了苯乙妥因和苯妥英钠在94例癫痫门诊患者中进行的双盲交叉试验。两组患者的癫痫发作频率无显著差异。文中特别讨论了比较两种疗效相似的抗惊厥药物时所面临的困难，尤其是在伦理问题、患者选择和试验设计方面。
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A comparison of phenytoin and pheneturide in patients with epilepsy: a double-blind cross-over trial.癫痫患者中苯妥英钠与苯乙妥因的比较：一项双盲交叉试验。
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本文引用的文献
1
Treatment of intractable temporal lobe epilepsy with pheneturide.用苯乙妥因治疗顽固性颞叶癫痫。
Acta Neurol Scand. 1967;43(5):580-6. doi: 10.1111/j.1600-0404.1967.tb05553.x.
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A rapid micro-method for determining four anti-convulsant drugs by gas-liquid chromatography.
Clin Chim Acta. 1973 Oct 12;48(2):135-41. doi: 10.1016/0009-8981(73)90358-6.
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Pheneturide in epilepsy: preliminary communication.苯乙妥因治疗癫痫：初步报告。
Br J Clin Pract. 1973 May;27(5):174-6.
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Comparative trial of diazepam and pheneturide in treatment of epilepsy.地西泮与苯乙妥因治疗癫痫的对比试验。
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