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抗癫痫药物治疗部分性发作和强直阵挛性发作的比较疗效

The comparative efficacy of antiepileptic drugs for partial and tonic-clonic seizures.

作者信息

Chadwick D, Turnbull D M

出版信息

J Neurol Neurosurg Psychiatry. 1985 Nov;48(11):1073-7. doi: 10.1136/jnnp.48.11.1073.

Abstract

Studies of the efficacy of anticonvulsant drugs are difficult to undertake and historically have been of poor quality. Randomised comparisons of drugs are few in number, and have failed to detect significant differences between drugs. This is surprising in view of the strong feelings that many clinicians have about the relative efficacy of the drugs they use. A review of the literature emphasises the need for further studies in this field.

摘要

抗惊厥药物疗效的研究很难开展,而且从历史上看质量都不高。药物的随机对照比较数量很少,并且未能发现不同药物之间的显著差异。鉴于许多临床医生对他们所使用药物的相对疗效有着强烈的看法,这一结果令人惊讶。文献综述强调了该领域进一步研究的必要性。

相似文献

本文引用的文献

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Early prognosis of epilepsy.癫痫的早期预后
Br Med J (Clin Res Ed). 1982 Dec 11;285(6356):1699-701. doi: 10.1136/bmj.285.6356.1699.
7
Controlled trials in epilepsy: a review.癫痫的对照试验:综述
Epilepsia. 1982 Oct;23(5):491-519. doi: 10.1111/j.1528-1157.1982.tb05437.x.

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