Abedin Z, Daniel W, Bloomfield D K
Jpn Heart J. 1982 Nov;23(6):897-903. doi: 10.1536/ihj.23.897.
To determine the effect of acute myocardial infarction (AMI) on serum and urinary activity of beta-galactosidase and beta-glucuronidase (lysosomal enzymes) 40 patients were studied. Eighteen patients had acute myocardial infarction and 22 were assigned as controls. Three of the 18 patients with acute myocardial infarction died within 5 to 10 days after hospitalization. Although the serum and urinary beta-glucuronidase and serum beta-galactosidase activity was higher in patients with acute myocardial infarction when compared with the control subjects these differences did not achieve statistical significance. However, the mean values of urinary beta-galactosidase in the control and acute MI groups were 158.68 and 333.3 nmol/mg creatinine/hr, respectively (p less than 0.046). These findings indicate that there is a significant increase in the urine beta-galactosidase activity during the early phases of acute myocardial infarction.
为了确定急性心肌梗死（AMI）对血清和尿液中β-半乳糖苷酶及β-葡萄糖醛酸酶（溶酶体酶）活性的影响，对40名患者进行了研究。18名患者患有急性心肌梗死，22名被指定为对照组。18名急性心肌梗死患者中有3人在住院后5至10天内死亡。尽管与对照组相比，急性心肌梗死患者血清和尿液中的β-葡萄糖醛酸酶以及血清β-半乳糖苷酶活性更高，但这些差异未达到统计学意义。然而，对照组和急性心肌梗死组尿液β-半乳糖苷酶的平均值分别为158.68和333.3 nmol/mg肌酐/小时（p<0.046）。这些发现表明，在急性心肌梗死早期，尿液β-半乳糖苷酶活性显著增加。
