人类胫前肌运动神经元的突触连接。
Synaptic connections to individual tibialis anterior motoneurones in man.
作者信息
Ashby P, Zilm D
出版信息
J Neurol Neurosurg Psychiatry. 1978 Aug;41(8):684-9. doi: 10.1136/jnnp.41.8.684.
Abstract
The characteristics of post-synaptic potentials in a single human motoneurone can be derived from the profiles of post-stimulus time histograms (PSTH) of that neurone when it is firing rhythmically. We have used this method to explore the synaptic connections to individual tibialis anterior motoneurones in man. Agonist group 1 volleys produced short latency excitation of 85% of tibialis anterior motoneurones probably representing the 1a EPSP. Excitation, at a latency of 70 ms, is attributed to a long loop reflex. Antagonist group 1 volleys produced short latency inhibition of 65% of tibialis anterior motoneurones probably representing the 1a IPSP. Excitation, at a latency of 97 ms, may represent spino-bulbo-spinal reflex. None of these effects are due to the excitation of cutaneous afferent nerve fibres.
摘要
单个运动神经元突触后电位的特征可从该神经元节律性放电时的刺激后时间直方图（PSTH）中推导得出。我们已运用此方法探究人类个体胫前运动神经元的突触连接。激动剂1组的阵发放电会使85%的胫前运动神经元产生短潜伏期兴奋，这可能代表Ia兴奋性突触后电位（EPSP）。潜伏期为70毫秒的兴奋归因于长环反射。拮抗剂1组的阵发放电会使65%的胫前运动神经元产生短潜伏期抑制，这可能代表Ia抑制性突触后电位（IPSP）。潜伏期为97毫秒的兴奋可能代表脊髓 - 延髓 - 脊髓反射。这些效应均非由皮肤传入神经纤维的兴奋所致。
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