大鼠免疫球蛋白δ重链基因：源自克隆cDNA的核苷酸序列。
Rat immunoglobulin delta heavy chain gene: nucleotide sequence derived from cloned cDNA.
作者信息
Sire J, Auffray C, Jordan B R
出版信息
Gene. 1982 Dec;20(3):377-86. doi: 10.1016/0378-1119(82)90206-2.
Rat immunoglobulin delta heavy-chain mRNA has been isolated. RNA blot analysis revealed that this mRNA with a length of 1.8 kb encodes for the secreted form of IgD. The corresponding cDNA was cloned in plasmid pBR322 and its sequence was determined. The hybrid plasmid contains a 775-bp insert comprising a partial C delta 1 sequence and complete C delta H, C delta 3, C delta DC and 3' untranslated sequences. Rat and mouse IgD amino acid sequences show striking homology in C delta 3 and C delta DC regions.
大鼠免疫球蛋白δ重链mRNA已被分离出来。RNA印迹分析表明，这种长度为1.8kb的mRNA编码分泌型IgD。相应的cDNA被克隆到质粒pBR322中并测定了其序列。该杂交质粒包含一个775bp的插入片段，其包含部分Cδ1序列以及完整的CδH、Cδ3、CδDC和3'非翻译序列。大鼠和小鼠的IgD氨基酸序列在Cδ3和CδDC区域显示出显著的同源性。
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