Spetzler R F, Wilson C B
J Neurosurg. 1978 Sep;49(3):393-7. doi: 10.3171/jns.1978.49.3.0393.
The authors review 39 patients with cerebrospinal fluid (CSF) leaks originating from the middle or posterior fossa. They evaluate the usefulness of preoperative investigative procedures, including cisternal radionuclide scanning and the deliberate increase of intracranial pressure. The results in this series emphasize the important role that abnormal CSF dynamics play in the recurrence of problematic cases of rhinorrhea or otorrhea. The following guidelines are recommended by the authors on the basis of their recent experience: 1) if hydrocephalus is present, if the cisternogram is abnormal, or if the CSF leak is intermittent and slight, the initial treatment should be insertion of a lumboperitoneal shunt; 2) if the leak is localized in the sellar or parasellar area, a transsphenoidal approach to obliterate the leak is advised; 3) if the CSF leak originates through a dural opening into the middle ear, an intracranial repair is indicated.
作者回顾了39例源于中颅窝或后颅窝的脑脊液(CSF)漏患者。他们评估了术前检查程序的实用性,包括脑池放射性核素扫描和故意增加颅内压。该系列研究结果强调了异常脑脊液动力学在鼻漏或耳漏问题病例复发中所起的重要作用。作者根据其近期经验推荐了以下指导原则:1)如果存在脑积水、脑池造影异常或脑脊液漏为间歇性且轻微,初始治疗应是插入腰大池腹腔分流管;2)如果漏口位于鞍区或鞍旁区域,建议采用经蝶入路来封闭漏口;3)如果脑脊液漏通过硬脑膜开口进入中耳,则需进行颅内修复。