Huston R K, Benda G I, Carlson C V, Shearer T R, Reynolds J W, Neerhout R C
JPEN J Parenter Enteral Nutr. 1982 Nov-Dec;6(6):507-10. doi: 10.1177/0148607182006006507.
A randomized prospective study of LBW infants was undertaken to evaluate the effect of parenteral lipid infusions upon their antioxidant systems. Ten babies received a parenteral nutrition regimen with lipid emulsion, and ten received a regimen without lipid. Although the addition of lipid emulsion to the total parenteral nutrition regimen led to a rise in vitamin E levels, the selenium levels fell in both groups. Neither group showed evidence of deficient antioxidant systems by the peroxide hemolysis test or thiobarbituric acid test. There did not seem to be any adverse effect of the lipid infusion upon the clinical course of the infants except for hyperlipidemia. There was a better weight gain in infants receiving lipid.
对低体重儿进行了一项随机前瞻性研究，以评估肠外输注脂质对其抗氧化系统的影响。10名婴儿接受了含脂质乳剂的肠外营养方案，另外10名婴儿接受了不含脂质的方案。尽管在全肠外营养方案中添加脂质乳剂会导致维生素E水平升高，但两组的硒水平均下降。通过过氧化物溶血试验或硫代巴比妥酸试验，两组均未显示抗氧化系统不足的证据。除高脂血症外，脂质输注似乎对婴儿的临床病程没有任何不良影响。接受脂质的婴儿体重增加更好。
