Suzuoka M, Katayama T, Monden K, Shimada Y, Hirano T, Kono Y, Ogasawara K, Bada K, Obaya M, Fujioka J, Takasan H
Gan To Kagaku Ryoho. 1982 Nov;9(11):1950-4.
Intra-arterial infusion chemotherapy was performed in 50 patients with cancer of the liver including 12 primary hepatoma and 38 metastatic cancers, at Kurashiki Central Hospital from December 1977 through December 1981. B.D. Fomocath 5 French catheter was inserted through the lateral femoral circumflex artery and advanced retrogradely to the common hepatic or proper hepatic artery using a loop catheter technique and the catheter was connected to the tube of infusion pump. The dose of 5-Fluorouracil and Mitomycin C was 250 mg per day and 4-10 mg once a week, respectively. The patients had average survival of 8.2 months in hepatoma and 4.8 months in metastatic tumor. The results were unfortunately not encouraging but this regimen occasionally provides excellent results and has no contraindication.
1977年12月至1981年12月期间，仓敷中央医院对50例肝癌患者进行了动脉内灌注化疗，其中包括12例原发性肝癌和38例转移性癌。使用5F的B.D. Fomocath导管经旋股外侧动脉插入，采用圈套导管技术逆行推进至肝总动脉或肝固有动脉，然后将导管连接至输液泵的管道。5-氟尿嘧啶和丝裂霉素C的剂量分别为每日250毫克和每周一次4-10毫克。原发性肝癌患者的平均生存期为8.2个月，转移性肿瘤患者为4.8个月。遗憾的是，结果并不令人鼓舞，但这种治疗方案偶尔会产生极佳的效果，且没有禁忌症。
