Farida Khatun U H, Khan M R, Ara F, Ahmed K, Choudhury S A
Bangladesh Med Res Counc Bull. 1982 Dec;8(2):68-71.
Thyroid functions were studied in eight children suffering from PEM. The assessment of thyroid functions were done by measuring serum T3 and T4 levels by radioimmunoassay. Both T3 and T4 levels in serum were significantly (P less than 0.001) reduced in PEM as compared to normal healthy children. These results suggest that thyroid functions are affected in PEM. The impairment of such functions may possibly be due to a deficiency of protein or to a blockade in the incorporation of iodine into thyroid hormone at some stage after iodide transport into the gland. The possibility of alteration of some biochemical or metabolic changes induced by PEM during biosynthesis of thyroid hormones cannot be excluded.
对8名患有蛋白质-能量营养不良（PEM）的儿童的甲状腺功能进行了研究。通过放射免疫测定法测量血清T3和T4水平来评估甲状腺功能。与正常健康儿童相比，PEM患儿血清中的T3和T4水平均显著降低（P<0.001）。这些结果表明，PEM会影响甲状腺功能。这种功能损害可能是由于蛋白质缺乏，或者是在碘转运到甲状腺后，在某个阶段碘掺入甲状腺激素的过程受阻。不能排除PEM在甲状腺激素生物合成过程中引起某些生化或代谢变化改变的可能性。
