Potish R, Adcock L, Jones T, Levitt S, Prem K, Savage J, Twiggs L
Gynecol Oncol. 1983 Feb;15(1):1-9. doi: 10.1016/0090-8258(83)90110-5.
From 1971 through 1981, 81 women received 4350 to 5075 rad to the periaortic lymph nodes as part of their primary management for carcinoma of the uterine cervix. While two patients developed chronic small bowel damage, only one required surgical intervention. Five-year disease-free survival was 40%. Approximately one-third of the first recurrences were within the pelvic and periaortic radiation portals, with the remainder in the lungs, liver, bones, abdomen, and supraclavicular lymph nodes. Radiation dose and volume guidelines are presented in order to minimize enteric morbidity.
从1971年到1981年,81名女性接受了4350至5075拉德的腹主动脉旁淋巴结照射,作为她们子宫颈癌初始治疗的一部分。虽然有两名患者出现了慢性小肠损伤,但只有一名需要手术干预。五年无病生存率为40%。首次复发中约三分之一发生在盆腔和腹主动脉旁放疗野内,其余发生在肺部、肝脏、骨骼、腹部和锁骨上淋巴结。文中给出了放射剂量和体积指南,以尽量减少肠道并发症。