Hacker N F, Nieberg R K, Berek J S, Leuchter R S, Lucas W E, Tamimi H K, Nolan J F, Moore J G, Lagasse L D
Gynecol Oncol. 1983 Feb;15(1):65-77. doi: 10.1016/0090-8258(83)90118-x.
Seven patients with superficially invasive vulvar cancer and lymph node metastases are reported. Histology of the primary tumor does not seem to correlate reliably with its metastatic potential in any individual case, though "spray," pseudoglandular, and small cell carcinomas may be particularly aggressive lesions. While wide local excision seems to be adequate treatment for the primary lesion, it is recommended that for lesions with greater than 1 mm of stromal invasion, bilateral inguinal-femoral lymphadenectomy should be performed for midline lesions, and at least ipsilateral inguinal-femoral lymphadenectomy should be performed for lateralized lesions.
报告了7例浅表浸润性外阴癌伴淋巴结转移的患者。在任何个别病例中，原发肿瘤的组织学表现似乎与其转移潜能并无可靠的相关性，不过“喷洒状”、假腺管状和小细胞癌可能是特别具有侵袭性的病变。虽然广泛局部切除似乎是原发灶的充分治疗方法，但对于间质浸润超过1mm的病变，对于中线病变建议行双侧腹股沟-股淋巴结清扫术，对于偏侧病变至少应行同侧腹股沟-股淋巴结清扫术。
