Jeffrey I, Royston P, Sowter C, Slavin G, Price A, Pomerance A, Goolamali S, Pinto D
J Clin Pathol. 1983 Jan;36(1):51-6. doi: 10.1136/jcp.36.1.51.
The relation between survival and histological features in 91 patients with malignant melanoma was studied and the results were analysed by Clayton's method for interpretation of censored survival data. There was a significant correlation between tumour thickness and survival. The risk of dying from malignant melanoma after 10 years of follow up was less than 15% if the primary tumour was less than 1.5 mm thick but more than 80% if the lesion was thicker than 8 mm. The type of melanoma, level of invasion, mitotic rate, and presence of ulceration also correlated with survival, but these variables are related to tumour thickness.
对91例恶性黑色素瘤患者的生存情况与组织学特征之间的关系进行了研究，并采用克莱顿法对截尾生存数据进行分析以得出结果。肿瘤厚度与生存情况之间存在显著相关性。如果原发肿瘤厚度小于1.5毫米，随访10年后死于恶性黑色素瘤的风险小于15%，但如果病灶厚度超过8毫米，该风险则超过80%。黑色素瘤的类型、浸润深度、有丝分裂率和溃疡情况也与生存情况相关，但这些变量与肿瘤厚度有关。
