Calonje E
Department of Dermatopathology, St John's Institute of Dermatology, St Thomas's Hospital, London, UK.
J Clin Pathol. 2000 Aug;53(8):587-90. doi: 10.1136/jcp.53.8.587.
The incidence of malignant melanoma has increased steadily over the past 30 years and this type of malignancy is the leading cause of death from cutaneous malignant disease. Cutaneous malignancies, including melanoma, can be detected at a very early stage and a cure is possible with prompt detection and treatment. In recent years, and mainly because of increased awareness of the early detection of melanoma, histopathologists have been exposed more and more to melanocytic lesions. Therefore, it is essential that histopathologists are able to provide a report to the clinician that conveys relevant information in a concise and precise manner. This paper provides a set of guidelines aimed at helping histopathologists with the gross and microscopic description and diagnosis of malignant melanoma.
在过去30年里,恶性黑色素瘤的发病率稳步上升,这种恶性肿瘤是皮肤恶性疾病致死的主要原因。包括黑色素瘤在内的皮肤恶性肿瘤能够在非常早期被检测出来,及时发现并治疗就有可能治愈。近年来,主要由于对黑色素瘤早期检测的认识提高,组织病理学家越来越多地接触到黑素细胞病变。因此,组织病理学家必须能够向临床医生提供一份报告,以简洁准确的方式传达相关信息。本文提供了一套指南,旨在帮助组织病理学家对恶性黑色素瘤进行大体和显微镜描述及诊断。