Wilcox W D, Carrigan T A, Dooley K J, Giddens D P, Dykes F D, Lazzara A, Ray J L, Ahmann P A
J Pediatr. 1983 Feb;102(2):294-8. doi: 10.1016/s0022-3476(83)80546-0.
Range-gated pulsed Doppler (RGPD) ultrasonography was utilized to study the effect of a patent ductus arteriosus (PDA) on carotid arterial blood flow in small preterm infants. Carotid arterial flow velocity studies were performed on 23 preterm infants, sampling right and left carotid arteries. Studies on seven infants after PDA ligation and on seven who developed no evidence of PDA were used as controls. A strong relationship was demonstrated between diastolic reversal in the carotid arteries and PDA. The results of this study indicate that the RGPD flow velocity curve from the carotid artery is more sensitive than M-mode echocardiography or clinical examination in detecting PDA, and that PDA in small preterm infants is associated with a distinct abnormality in the carotid arterial flow pattern.
采用距离选通脉冲多普勒（RGPD）超声检查法研究动脉导管未闭（PDA）对小早产儿颈动脉血流的影响。对23例早产儿进行颈动脉血流速度研究，采集左右颈动脉样本。对7例PDA结扎术后的婴儿和7例未发现PDA迹象的婴儿进行的研究用作对照。结果表明，颈动脉舒张期血流逆转与PDA之间存在密切关系。本研究结果表明，在检测PDA方面，来自颈动脉的RGPD血流速度曲线比M型超声心动图或临床检查更敏感，并且小早产儿的PDA与颈动脉血流模式的明显异常有关。
