Grimes H G, Nosal R A, Gallagher J C
Obstet Gynecol. 1983 Feb;61(2):174-80.
This study was undertaken to investigate 24 cases of ovarian pregnancy identified by retrospective analysis of 148,734 deliveries at 6 hospitals between 1952 and 1980, and to review pertinent literature. Although ovarian pregnancy is rare, it was shown to occur 4 times more frequently than previously believed--on the order of 1 per 7000 deliveries and slightly less than 3% of all ectopic pregnancies. Awareness of the possibility of ovarian pregnancy and closer histologic examination of surgical specimens are critical factors for increased recognition. The use of intrauterine contraceptive devices was not associated with an absolute increase in occurrence of ovarian pregnancy. More than half the cases involved a history of previous reproductive system pathology or infertility. Clinical presentations of ovarian and tubal pregnancies are similar and differentiation can be made only after microscopic examination of tissue specimens. Even then, diagnosis of primary ovarian pregnancy may be elusive due to increasing tissue destruction and greater use of conservative surgical procedures. When the organized diagnostic approach should be followed. Culdocentesis should be performed whenever hemoperitoneum is suspected. The preferred therapeutic procedure is ovarian cystectomy or ovarian wedge resection. No maternal mortality occurred in any of the cases reviewed. An extremely rare case of ovarian pregnancy following vaginal hysterectomy is presented.
本研究通过对1952年至1980年间6家医院148734例分娩进行回顾性分析,对24例卵巢妊娠病例展开调查,并查阅相关文献。尽管卵巢妊娠罕见,但研究表明其发生率比之前认为的高出4倍,约为每7000例分娩中有1例,占所有异位妊娠的比例略低于3%。认识到卵巢妊娠的可能性以及对手术标本进行更细致的组织学检查是提高识别率的关键因素。宫内节育器的使用与卵巢妊娠发生率的绝对增加并无关联。超过半数的病例有既往生殖系统病变或不孕史。卵巢妊娠和输卵管妊娠的临床表现相似,只有在对组织标本进行显微镜检查后才能做出区分。即便如此,由于组织破坏加剧以及保守性手术操作的更多应用,原发性卵巢妊娠的诊断可能仍难以明确。此时应遵循有条理的诊断方法。每当怀疑有腹腔积血时,都应进行后穹窿穿刺。首选的治疗方法是卵巢囊肿切除术或卵巢楔形切除术。在所审查的任何病例中均未发生孕产妇死亡。本文还介绍了1例极为罕见的阴道子宫切除术后卵巢妊娠病例。