Krebs H B, Goplerud D R
Obstet Gynecol. 1983 Mar;61(3):327-30.
The surgical management of 118 instances of bowel obstruction associated with advanced ovarian cancer in 98 patients is reviewed. In 12% of the treatment episodes, patients were found to have inoperable disease at laparotomy. Surgical correction of the intestinal obstruction was associated with an operative mortality of 12%. In 35% of the cases, patients did not benefit from surgical treatment, as they died within 8 weeks of the operation. Patients' age, nutritional status, tumor spread, presence of ascites, and the type and amount of prior chemotherapy and/or radiation therapy correlate well with the patients' prognosis. A simple prognostic index based upon these 6 criteria is suggested as a means of predicting the possible benefit from surgical intervention.
回顾了98例晚期卵巢癌伴肠梗阻患者的118例手术治疗情况。在12%的治疗过程中,患者在剖腹手术时被发现患有无法手术的疾病。肠梗阻的手术矫正与12%的手术死亡率相关。在35%的病例中,患者未从手术治疗中获益,因为他们在手术后8周内死亡。患者的年龄、营养状况、肿瘤扩散、腹水的存在以及先前化疗和/或放疗的类型和剂量与患者的预后密切相关。建议基于这6个标准的简单预后指数作为预测手术干预可能获益的一种方法。