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本文引用的文献

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Long-term Postprocedural Outcomes of Palliative Emergency Stenting vs Stoma in Malignant Large-Bowel Obstruction.姑息性紧急支架置入术与造口术治疗恶性大肠梗阻的长期术后结局
JAMA Surg. 2017 May 1;152(5):429-435. doi: 10.1001/jamasurg.2016.5043.
2
How to decide on stent insertion or surgery in colorectal obstruction?如何决定结直肠梗阻时是置入支架还是进行手术?
World J Gastrointest Surg. 2016 Jan 27;8(1):84-9. doi: 10.4240/wjgs.v8.i1.84.
3
Surgery for the resolution of symptoms in malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer.手术治疗晚期妇科和胃肠道癌症恶性肠梗阻的症状缓解。
Cochrane Database Syst Rev. 2016 Jan 4;2016(1):CD002764. doi: 10.1002/14651858.CD002764.pub2.
4
Management of intestinal obstruction in advanced malignancy.晚期恶性肿瘤肠梗阻的管理
Ann Med Surg (Lond). 2015 Aug 1;4(3):264-70. doi: 10.1016/j.amsu.2015.07.018. eCollection 2015 Sep.
5
Large-Bowel Obstruction in the Adult: Classic Radiographic and CT Findings, Etiology, and Mimics.成人大肠梗阻:经典影像学表现和 CT 表现、病因和类症鉴别。
Radiology. 2015 Jun;275(3):651-63. doi: 10.1148/radiol.2015140916.
6
Recommendations for bowel obstruction with peritoneal carcinomatosis.腹膜癌病所致肠梗阻的治疗建议。
J Pain Symptom Manage. 2014 Jul;48(1):75-91. doi: 10.1016/j.jpainsymman.2013.08.022. Epub 2014 May 4.
7
A scoring system for the prognosis and treatment of malignant bowel obstruction.一种用于预测和治疗恶性肠梗阻的评分系统。
Surgery. 2012 Oct;152(4):747-56; discussion 756-7. doi: 10.1016/j.surg.2012.07.009. Epub 2012 Aug 26.
8
Malignant bowel obstruction in advanced cancer patients: epidemiology, management, and factors influencing spontaneous resolution.晚期癌症患者的恶性肠梗阻:流行病学、处理方法以及影响自发性缓解的因素。
Cancer Manag Res. 2012;4:159-69. doi: 10.2147/CMAR.S29297. Epub 2012 Jun 13.
9
Malignant bowel obstruction: individualized treatment near the end of life.恶性肠梗阻:生命末期的个体化治疗。
Cleve Clin J Med. 2011 Mar;78(3):197-206. doi: 10.3949/ccjm.78a.10052.
10
Malignant bowel obstruction: natural history of a heterogeneous patient population followed prospectively over two years.恶性肠梗阻:前瞻性随访两年的异质患者人群的自然史。
J Pain Symptom Manage. 2011 Feb;41(2):412-20. doi: 10.1016/j.jpainsymman.2010.05.007. Epub 2010 Dec 4.

晚期癌症中的肠梗阻

Bowel obstruction in advanced cancer.

作者信息

Ferraz Gonçalves José António, Faria Magda, Araújo Vânia, Monteiro Ana Raquel, Silva Ana Vítor, Jamal Sheila, Moutinho Adelaide

机构信息

Palliative Care Service, Instituto Português de Oncologia, R. Dr. António Bernardino de Almeida, Porto, Portugal.

出版信息

Porto Biomed J. 2019 Jul 2;4(6):e41. doi: 10.1097/j.pbj.0000000000000041. eCollection 2019 Nov-Dec.

DOI:10.1097/j.pbj.0000000000000041
PMID:33501393
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7819537/
Abstract

PURPOSE

Assessment of treatment of cancer patients with bowel obstruction, identification of prognostic factors, and assessment of reference to palliative care.

METHODS

Records of patients with a diagnosis of bowel obstruction over a 6-month (January-June 2013) period were reviewed.

RESULTS

Seventy-five patients were diagnosed with bowel obstruction. Fifty-one (68%) were female and the median age was 65 years (27-100). The most frequent cancer was colorectal, 30 (40%), followed by gynecological cancer, 20 (27%). Forty-three (57%) patients underwent conservative treatment; 26 (35%) underwent surgery; and 6 (8%) had a stent placement. In 68 (91%), the bowel obstruction was resolved. Three years after the bowel obstruction episode, 15 (20%) patients were still alive. An analysis of the possible association of variables recorded with mortality was carried out, and for death at the first admission, only the resolution of the obstruction was significant ( < .001); for the 3-year survival the significant factors were hemoglobin >10.7 g/dL ( < .001) and ascites ( = .001) at the time of obstruction. Thirty-seven (49%) patients were referred to palliative care.

CONCLUSIONS

Although bowel obstruction in cancer patients is usually associated with a short life expectancy, some patients have relatively long survivals. Only about half of the patients were referred to palliative care.

摘要

目的

评估癌症肠梗阻患者的治疗情况,确定预后因素,并评估姑息治疗的参考情况。

方法

回顾了2013年1月至6月这6个月期间诊断为肠梗阻的患者记录。

结果

75例患者被诊断为肠梗阻。51例(68%)为女性,中位年龄为65岁(27 - 100岁)。最常见的癌症是结直肠癌,30例(40%),其次是妇科癌症,20例(27%)。43例(57%)患者接受了保守治疗;26例(35%)接受了手术;6例(8%)进行了支架置入。68例(91%)患者的肠梗阻得到缓解。肠梗阻发作3年后,15例(20%)患者仍存活。对记录的变量与死亡率的可能关联进行了分析,对于首次入院时的死亡情况,只有梗阻的缓解具有显著性(<0.001);对于3年生存率,显著因素是梗阻时血红蛋白>10.7g/dL(<0.001)和腹水(=0.001)。37例(49%)患者被转介至姑息治疗。

结论

尽管癌症患者的肠梗阻通常与预期寿命较短相关,但一些患者存活时间相对较长。只有约一半的患者被转介至姑息治疗。