Francke E
Postgrad Med. 1983 Feb;73(2):347, 350-2, 354.
"New" diseases continue to crop up. One of the most spectacular of these is Legionnaires' disease, first diagnosed after an epidemic in Philadelphia in 1976. Analysis of stored serums, however, has shown the causative agent, Legionella pneumophila, to be the culprit in epidemics of pneumonia occurring as early as 1947. The disease has a spectrum of presentations ranging from a self-limited syndrome of myalgias and nonproductive cough with a 24-hour incubation period to a severe pneumonia with diarrhea and delirium and up to 30% mortality. Therapy consists of erythromycin with or without rifampin. One reviewer said, "I found Dr Francke's article . . . to be an informative treatise on a fascinating subject."
“新型”疾病不断出现。其中最引人注目的一种是军团病，1976年在费城爆发疫情后首次被诊断出来。然而，对储存血清的分析表明，致病因子嗜肺军团菌早在1947年就已在肺炎疫情中作祟。该疾病有一系列表现，从潜伏期为24小时的以肌痛和干咳为主的自限性综合征，到伴有腹泻和谵妄且死亡率高达30%的严重肺炎。治疗方法是使用红霉素，可加用或不加用利福平。一位评论家说：“我发现弗兰克博士的文章……是一篇关于一个引人入胜主题的内容丰富的论文。”
