Johnson D E, O'Connell J R
Urology. 1983 Jan;21(1):42-5. doi: 10.1016/0090-4295(83)90120-6.
The clinical and morphologic features in 29 cases of primary carcinoma of the female urethra were reviewed. Only 2 of 12 patients treated with radiotherapy are known to have failed; one is dead of disease at one year, and the other is alive with local recurrence at two years. We consider these results sufficiently satisfactory to warrant the continued use of radiotherapy in early-stage lesions, as well as in selected patients who have infiltrating carcinoma. Integrated therapy consisting of 5,000 rad/25 fractions/five weeks, followed in six weeks by radical cystourethrectomy, was used in 7 patients. The low morbidity and absence of operative mortality recommend continuation of this aggressive approach for infiltrating tumors in selected patients.
回顾了29例女性尿道原发性癌的临床和形态学特征。已知接受放疗的12例患者中仅有2例治疗失败；1例在1年后死于疾病，另1例在2年后仍存活但有局部复发。我们认为这些结果足够令人满意，足以保证在早期病变以及部分浸润性癌患者中继续使用放疗。7例患者采用了综合治疗，即5000拉德/25次分割/5周，6周后行根治性膀胱尿道切除术。低发病率和无手术死亡率表明对部分浸润性肿瘤患者继续采用这种积极的治疗方法是可行的。
