Spontaneous expression of the chromosome fragile site fra(10)(q25).
作者信息
Taylor A M, Bundey S
出版信息
Am J Hum Genet. 1983 Jan;35(1):123-5.
Abstract
We report the spontaneous expression of the chromosome fragile site at 10q25 in a child with progressive cerebellar ataxia and in her phenotypically normal brother and father. Expression of this fragile site was increased in all three individuals by addition of bromodeoxyuridine (BrdU) to the medium. This fragile site has previously been described only following growth of cells in BrdU.
摘要
相似文献
1
Spontaneous expression of the chromosome fragile site fra(10)(q25).
Am J Hum Genet. 1983 Jan;35(1):123-5.
2
Heritable fragile sites on human chromosomes. VII. Children homozygous for the BrdU-requiring fra(10)(q25) are phenotypically normal.
Am J Hum Genet. 1981 Nov;33(6):946-9.
3
4
A new family with fra(10)(q25): spontaneous expression and 100% expression with 100 microM BrdU.
Am J Med Genet. 1985 Aug;21(4):643-8. doi: 10.1002/ajmg.1320210405.
5
Enhanced expression of chromosome fragile site 10q25 in chronic myelogenous leukemia.
Am J Med Genet. 1985 Jun;21(2):347-50. doi: 10.1002/ajmg.1320210217.
6
7
Spontaneous expression of fra(10)(q25) in bone marrow from a patient with agranulocytosis.
Am J Med Genet. 1988 Nov;31(3):663-7. doi: 10.1002/ajmg.1320310322.
8
[Heritable fragile sites on human chromosomes: characterization of a new BrdU-dependent site in 12q24].
Pathologica. 1983;75 Suppl:324-8.
9
Bromodeoxyuridine induces chromosomal fragile sites in the canine genome.溴脱氧尿苷可诱导犬类基因组中的染色体脆性位点。
Am J Med Genet. 1993 Apr 15;46(2):198-202. doi: 10.1002/ajmg.1320460220.
10
Fra(10)(q25): the BrdU effect is substitution-dependent.10号染色体长臂2区5带脆性位点（Fra(10)(q25)）：5-溴脱氧尿嘧啶核苷（BrdU）效应取决于替代作用。
Am J Hum Genet. 1985 Jan;37(1):208-14.
引用本文的文献
1
2
Fra(10)(q25): the BrdU effect is substitution-dependent.10号染色体长臂2区5带脆性位点（Fra(10)(q25)）：5-溴脱氧尿嘧啶核苷（BrdU）效应取决于替代作用。
Am J Hum Genet. 1985 Jan;37(1):208-14.
3
Expression of fra(10)(q25) in peripheral blood and bone marrow in familial neutropenia.家族性中性粒细胞减少症患者外周血及骨髓中fra(10)(q25)的表达
J Med Genet. 1988 Apr;25(4):238-42. doi: 10.1136/jmg.25.4.238.
4
A BrdU-requiring fragile site on chromosome 12.位于12号染色体上一个需要溴脱氧尿苷的脆性位点。
Hum Genet. 1988 Feb;78(2):183-5. doi: 10.1007/BF00278193.
本文引用的文献
1
Heritable fragile sites and lymphocyte culture medium containing BrdU.可遗传的脆性位点和含有溴脱氧尿苷的淋巴细胞培养基。
Am J Hum Genet. 1980 Jul;32(4):628-9.
2
Heritable fragile sites on human chromosomes. V. A new class of fragile site requiring BrdU for expression.人类染色体上的遗传性脆性位点。V. 一类新的需要5-溴脱氧尿嘧啶核苷来表达的脆性位点。
Am J Hum Genet. 1980 Jul;32(4):542-8.
3
Heritable fragile sites on human chromosomes. VII. Children homozygous for the BrdU-requiring fra(10)(q25) are phenotypically normal.
Am J Hum Genet. 1981 Nov;33(6):946-9.
4
Familial spastic ataxia: occurrence in childhood.家族性痉挛性共济失调：在儿童期的发生情况。
Neurology. 1977 Jun;27(6):520-6. doi: 10.1212/wnl.27.6.520.
5
Heritable fragile sites on human chromosomes II. Distribution, phenotypic effects, and cytogenetics.人类染色体上的遗传性脆性位点II。分布、表型效应及细胞遗传学
Am J Hum Genet. 1979 Mar;31(2):136-48.
6
Heritable fragile sites on human chromosomes I. Factors affecting expression in lymphocyte culture.人类染色体上的遗传性脆性位点。I. 影响淋巴细胞培养中表达的因素。
Am J Hum Genet. 1979 Mar;31(2):125-35.
Zotero 插件