Demeter S L, Fuenning C
Angiology. 1983 Jan;34(1):70-7. doi: 10.1177/000331978303400109.
Fibrinolytic agents have been advocated for the treatment of massive pulmonary emboli. The usual mode of infusion is via a peripheral vein. Theoretically, infusion into the pulmonary artery would be expected to be more efficacious. A case representing the failure of intra-pulmonary artery infusion of fibrinolytic agents is presented. However, a literature review suggests that this mode of therapy may achieve a greater success in clot lysis than does peripheral infusion. Additionally, this form of treatment may allow the clinician to lower the administered dose which may represent an advantage to the patient.
纤维蛋白溶解剂已被提倡用于治疗大面积肺栓塞。通常的输注方式是通过外周静脉。从理论上讲，注入肺动脉预计会更有效。本文介绍了一例肺动脉内注入纤维蛋白溶解剂失败的病例。然而，文献综述表明，这种治疗方式在血栓溶解方面可能比外周输注更成功。此外，这种治疗形式可能使临床医生能够降低给药剂量，这对患者来说可能是一个优势。
