Lindhagen A, Bergqvist D, Hallböök T, Efsing H O
Ann Surg. 1983 Feb;197(2):215-9. doi: 10.1097/00000658-198302000-00015.
The 125I-fibrinogen uptake test (FUT) has been widely used in the past decade to detect postoperative thrombosis. FUT has been shown to correlate well with phlebography, and positive FUT is associated with a high frequency of pulmonary embolism. The long-term venous function of the leg after FUT-detected postoperative thrombosis, however, is inadequately documented. In 179 patients who had been studied after operation with FUT, a follow-up evaluation of FUT as an indicator of risk for development of deep venous insufficiency was made four to five years later. The patients replied to a questionnaire, were clinically examined, and underwent venous strain-gauge plethysmography, venous pressure measurement, and, in some cases, phlebography. No statistically significant differences were found in any of the parameters between legs that had been FUT-positive and those that were FUT-negative at the time of the operation. The frequency of deep venous insufficiency thus was equal in FUT-positive and FUT-negative legs. It was also independent of the site of FUT-detected thrombus in the leg.
过去十年间，¹²⁵I - 纤维蛋白原摄取试验（FUT）被广泛用于检测术后血栓形成。研究表明，FUT与静脉造影结果具有良好的相关性，FUT结果呈阳性与肺栓塞的高发生率相关。然而，关于FUT检测出术后血栓形成后腿部的长期静脉功能，相关记录并不充分。在179例接受FUT术后检查的患者中，于术后四到五年对FUT作为深静脉功能不全发生风险指标进行了随访评估。患者需回复问卷，并接受临床检查、静脉应变计体积描记法、静脉压力测量，部分患者还接受了静脉造影。在手术时FUT结果为阳性的腿部与FUT结果为阴性的腿部之间，未发现任何参数存在统计学上的显著差异。因此，FUT结果为阳性和阴性的腿部发生深静脉功能不全的频率相同。此外，其与FUT检测出的腿部血栓部位无关。
