Browse N L, Clemenson G, Thomas M L
Br Med J. 1980 Nov 1;281(6249):1167-70. doi: 10.1136/bmj.281.6249.1167.
One hundred and thirty legs of 67 patients were examined 5-10 years after the patient had suffered a phlebographically proved deep-vein thrombosis. Forty-seven of the limbs were normal at the time of the phlebogram, 83 contained thrombus. There was little correlation between the phlebographic severity of the thrombus and the late symptoms and signs: 32% of the legs with no thrombosis had symptoms, while 33% of the legs which had suffered severe thrombosis had no symptoms. Postphlebitic symptoms were more common in legs with aging thrombus at the time of phlebography, but upper limit of the thrombus, the age of the patient, and preexisting symptoms did not affect the incidence of late sequelae. The development of a "postphlebitic leg" does not depend solely on the extent of the initial thrombosis and can apparently develop in the absence of thrombosis.
对67例患者的130条腿进行了检查,这些患者在经静脉造影证实患有深静脉血栓形成5至10年后接受检查。在静脉造影时,47条肢体正常,83条含有血栓。血栓的静脉造影严重程度与晚期症状和体征之间几乎没有相关性:32%无血栓的腿有症状,而33%患有严重血栓的腿无症状。静脉造影时伴有陈旧血栓的腿中,静脉炎后症状更常见,但血栓的上限、患者年龄和既往症状并不影响晚期后遗症的发生率。“静脉炎后综合征腿”的发生并不完全取决于初始血栓形成的范围,显然在无血栓的情况下也可能发生。