Moroz V M, Bures J
Brain Res. 1983 Jan 24;259(2):298-300. doi: 10.1016/0006-8993(83)91262-3.
Latencies of acoustically and visually signalled lateralized ballistic reaching were examined in rats with implanted electrodes in the caudate nuclei (Cd). Single pulse stimulation of Cd coinciding with CS onset increased the reach latency from 180 to 300 ms. Stimulation of Cd contralateral to the preferred forepaw was more disruptive than stimulation of ipsilateral Cd and the interference threshold was lower for Cd stimuli applied 100 ms after CS onset. Since reaching latencies were only moderately prolonged (by 85 ms) after electrolytic lesion of ipsilateral dentate nucleus. Cd stimulation does not only disrupt cerebellar preprogramming, but has a more general interfering effect.
在尾状核(Cd)植入电极的大鼠中,检测了声音和视觉信号提示的单侧弹道式伸手动作的潜伏期。与条件刺激(CS)开始同时进行的Cd单脉冲刺激将伸手潜伏期从180毫秒增加到300毫秒。对偏好前爪对侧的Cd进行刺激比同侧Cd刺激更具干扰性,并且在CS开始后100毫秒施加的Cd刺激的干扰阈值更低。由于同侧齿状核电解损伤后伸手潜伏期仅适度延长(延长85毫秒)。Cd刺激不仅会破坏小脑的预编程,而且具有更广泛的干扰作用。