Lapierre G, Pevonka M P, Stewart R B, Yost R L
Drug Intell Clin Pharm. 1983 Jan;17(1):39-44. doi: 10.1177/106002808301700107.
Treatment of hypertension in the elderly has recently received increased attention. Both systolic and systolic plus diastolic hypertension are risk factors for cardiovascular and cerebrovascular diseases in patients older than age 65, but the value of antihypertensive therapy in reducing morbidity and mortality has not been adequately studied. The authors evaluated the appropriateness of antihypertensive therapy prescribed for elderly patients in a skilled nursing home and determined the effect reductions in antihypertensive therapy had upon the function and mental status of these patients. Of the 120 patients surveyed, 26.7 percent were found to have a diagnosis of hypertension, and 1/3 of these patients were not receiving any medications at the time of the study. Assessment of the remaining treated patients resulted in a recommendation to alter therapy in 43 percent of the cases. Results from this study suggest that periodic assessment of antihypertensive therapy in long-term care facilities should be considered.
老年人高血压的治疗近来受到了更多关注。收缩期高血压以及收缩期加舒张期高血压都是65岁以上患者发生心脑血管疾病的危险因素，但降压治疗在降低发病率和死亡率方面的价值尚未得到充分研究。作者评估了一家专业疗养院为老年患者开具的降压治疗的合理性，并确定了降压治疗减量对这些患者功能和精神状态的影响。在接受调查的120名患者中，26.7%被诊断患有高血压，其中三分之一的患者在研究时未接受任何药物治疗。对其余接受治疗的患者进行评估后，43%的病例建议调整治疗方案。这项研究的结果表明，应考虑对长期护理机构中的降压治疗进行定期评估。
