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[关于搭载在“宇宙-690”卫星上进行太空飞行的大鼠消化器官的组织化学研究]

[Histochemical study of the digestive organs of rats on board for the space flight of the satellite "Cosmos-690"].

作者信息

Shubich M G, Goriacheva L L, Dudetskiĭ V I, Lutsenko N M, Mogil'naia G M

出版信息

Kosm Biol Aviakosm Med. 1978 Jul-Aug;12(4):41-6.

PMID:682559
Abstract

The digestive organs of rats exposed to a combined effect of space flight factors and irradiation were examined. The surface and foveal epithelium of the stomach as well as mucocytes of the fundal glands showed a drastically reduced content of the neutral carbohydrate component. The foveal epithelium and mucocytes of fundal necks also exhibited a significant decrease of the sulfomucin content. The large and small intestines showed a lowered amount of goblet-cells and their secretion. Pancreatic acinar cells displayed different changes in the content of enzymic proteins having cation properties. The above histochemical changes did not return to normal 36 days after irradiation and 26--27 days after readaptation to the Earth environment.

摘要

对受到太空飞行因素和辐射综合作用的大鼠的消化器官进行了检查。胃的表面和小凹上皮以及胃底腺的黏液细胞中中性碳水化合物成分的含量大幅降低。胃底颈部的小凹上皮和黏液细胞中硫黏液素的含量也显著减少。大肠和小肠中杯状细胞的数量及其分泌物减少。胰腺腺泡细胞中具有阳离子特性的酶蛋白含量出现不同变化。上述组织化学变化在辐射后36天以及重新适应地球环境后26 - 27天仍未恢复正常。

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