[Role of the gravitation factor in the development of changes in the digestive system].

The functional state of the gastro-intestinal system of rats aboard of "Cosmos-782", "Cosmos-936" and "Cosmos-1129", was studied. The long-term exposure to zero-gravity resulted in activation of proteolytic enzymes, decrease of carbohydrases and redistribution of lipolytic activities in gastro-intestinal organs. Use of artificial gravity during the flights produced a favourable effect on the proteolytic enzymes.