有证据表明存在一种酶，它能从专门设计用于抑制和定量胰蛋白酶的活性位点滴定剂上裂解胍基苯甲酸部分。 - Suppr

Suppr

超能文献

Evidence for an enzyme which cleaves the guanidinobenzoate moiety from active-site titrants specifically designed to inhibit and quantify trypsin.

作者信息

Steven F S, Al-Ahmad R K

出版信息

Eur J Biochem. 1983 Feb 1;130(2):335-9. doi: 10.1111/j.1432-1033.1983.tb07157.x.

DOI:10.1111/j.1432-1033.1983.tb07157.x

PMID:6825699

Abstract

摘要

相似文献

Evidence for an enzyme which cleaves the guanidinobenzoate moiety from active-site titrants specifically designed to inhibit and quantify trypsin.有证据表明存在一种酶，它能从专门设计用于抑制和定量胰蛋白酶的活性位点滴定剂上裂解胍基苯甲酸部分。

Eur J Biochem. 1983 Feb 1;130(2):335-9. doi: 10.1111/j.1432-1033.1983.tb07157.x.

Further inhibition studies on guanidinobenzoatase, a trypsin-like enzyme associated with tumour cells.对胍基苯甲酸酶（一种与肿瘤细胞相关的类胰蛋白酶）的进一步抑制研究。

J Enzyme Inhib. 1987;1(3):187-201. doi: 10.3109/14756368709020116.

The enzyme capable to cleave trypsin active site titrant as substrate is a carboxylesterase with electrophoretic mobility similar to albumin.能够切割以胰蛋白酶活性位点滴定剂为底物的酶是一种电泳迁移率与白蛋白相似的羧酸酯酶。

Acta Biochim Biophys Hung. 1990;25(1-2):57-65.

The design of fluorescent probes which bind to the active centre of guanidinobenzoatase. Application to the location of cells possessing this enzyme.

Eur J Biochem. 1985 May 15;149(1):35-40. doi: 10.1111/j.1432-1033.1985.tb08889.x.

Inhibition of guanidinobenzoatase by a substrate for trypsin-like enzymes.胰蛋白酶样酶的一种底物对胍基苯甲酸酶的抑制作用。

J Enzyme Inhib. 1988;2(3):209-14. doi: 10.3109/14756368809040727.

Determiniation of trypsin-inhibitor complex dissociation by use of the active site titrant, p-nitrophenyl p'-guanidinobenzoate.使用活性位点滴定剂对硝基苯基对'-胍基苯甲酸酯测定胰蛋白酶抑制剂复合物的解离

Biochemistry. 1970 Mar 17;9(6):1428-33. doi: 10.1021/bi00808a018.

Automated assay for alpha 1-antitrypsin with N-alpha-benzoyl-DL-arginine-p-nitroanilide as trypsin substrate and standardized with p-nitrophenyl-p'-guanidinobenzoate as titrant for trypsin active sites.以N-α-苯甲酰-DL-精氨酸对硝基苯胺为胰蛋白酶底物，以对硝基苯基-p'-胍基苯甲酸酯为胰蛋白酶活性位点滴定剂进行标准化的α1-抗胰蛋白酶自动化检测。

Clin Chem. 1982 May;28(5):1108-12.

Evidence for exchange of inhibitors which bind to the active site of trypsin. Displacement of one inhibitor with a competitive inhibitor.与胰蛋白酶活性位点结合的抑制剂交换的证据。一种竞争性抑制剂对另一种抑制剂的取代。

Biochim Biophys Acta. 1981 Dec 15;662(2):190-5. doi: 10.1016/0005-2744(81)90029-2.

Catalysis by serine proteases and their zymogens. A study of acyl intermediates by circular dichroism.丝氨酸蛋白酶及其酶原的催化作用。通过圆二色性对酰基中间体的研究。

Biochemistry. 1975 Nov 18;14(23):5088-94. doi: 10.1021/bi00694a010.

p-Nitrophenyl-p'-guanidinobenzoate HCl: a new active site titrant for trypsin.对硝基苯基-对'-胍基苯甲酸盐酸盐：一种用于胰蛋白酶的新型活性位点滴定剂。

Biochem Biophys Res Commun. 1967 Nov 30;29(4):508-14. doi: 10.1016/0006-291x(67)90513-x.

引用本文的文献

Studies on the activity of a protease associated with cells at the advancing edge of human tumour masses in frozen sections.关于冷冻切片中人类肿瘤块前沿与细胞相关的一种蛋白酶活性的研究。

Br J Cancer. 1988 Jul;58(1):57-60. doi: 10.1038/bjc.1988.161.

A study of guanidinobenzoatase during development of mesothelioma induced in the rat by fibrous erionite.由纤维水硅钙石诱发大鼠间皮瘤过程中胍基苯甲酸酶的研究。

Br J Cancer. 1988 Nov;58(5):610-3. doi: 10.1038/bjc.1988.269.

The inhibition of a tumour cell surface protease in vivo and its re-activation by oxidation.体内肿瘤细胞表面蛋白酶的抑制作用及其通过氧化实现的重新激活。

Br J Cancer. 1988 Feb;57(2):160-4. doi: 10.1038/bjc.1988.33.

The status of trypsin-like enzymes in squamous-cell carcinoma of the head and neck region.头颈部鳞状细胞癌中类胰蛋白酶的状况。

J Cancer Res Clin Oncol. 1990;116(1):57-64. doi: 10.1007/BF01612641.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验