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A radioimmunoassay for tauro-beta-muricholic acid suitable for use with isolated rat liver cells.

作者信息

Botham K M, Boyd G S, Williamson D, Beckett G J

出版信息

FEBS Lett. 1983 Jan 10;151(1):19-21. doi: 10.1016/0014-5793(83)80333-0.

DOI:10.1016/0014-5793(83)80333-0
PMID:6825837
Abstract

A new radioimmunoassay which can be used to measure the amounts of tauro-beta-muricholic acid produced by isolated rat hepatocytes in vitro is described. Cross reactivities of other bile acids known to be present in rat liver with the antiserum used in the assay were not sufficient to interfere with the measurement of tauro-beta-muricholic acid. Exogenous taurochenodeoxycholic acid was metabolised by isolated rat hepatocytes concurrently with the appearance of tauro-beta-muricholic acid in the cell.

摘要

相似文献

1
A radioimmunoassay for tauro-beta-muricholic acid suitable for use with isolated rat liver cells.
FEBS Lett. 1983 Jan 10;151(1):19-21. doi: 10.1016/0014-5793(83)80333-0.
2
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Tauro alpha-muricholate is as effective as tauro beta-muricholate and tauroursodeoxycholate in preventing taurochenodeoxycholate-induced liver damage in the rat.牛磺α-鼠胆酸盐在预防牛磺鹅去氧胆酸盐诱导的大鼠肝损伤方面与牛磺β-鼠胆酸盐及牛磺熊去氧胆酸盐效果相当。
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8
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9
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