Usala S J, Schumacher G F
Fertil Steril. 1983 Mar;39(3):304-9. doi: 10.1016/s0015-0282(16)46876-7.
Cervicovaginal fluid that accumulates in the upper vagina and posterior fornix can be quantitatively correlated with the presumably fertile and infertile phases of the menstrual cycle. With a newly developed Volumetric Vaginal Aspirator that women self-administer, cervicovaginal fluid can be sampled on a daily basis and the sample volume or sample weight recorded. In a total of 18 cycles from 7 different subjects there was a striking 3- to 30-fold increase in sample volume or sample weight above early follicular phase levels that preceded the shift in basal body temperature (BBT) at midcycle. The maximum of sample volume or sample weight near midcycle was defined as "Volume Peak" or "Weight Peak." The magnitude of the Volume Peak or Weight Peak varied in the individual subjects and was between 400 and 1500 microliters or mg. The Volume Peak or Weight Peak generally occurred 1 to 2 days before or on the day of presumptive ovulation. With the BBT shift to luteal phase levels, the sample volume or sample weight sharply declined to early follicular phase levels. The results suggest that changes in sample volume or sample weight of cervicovaginal fluid measured with the self-applicable Volumetric Vaginal Aspirator can be used as an objective basis for approaches to natural family planning and for the assessment of optimal conditions for conception.
积聚在上阴道和后穹窿的宫颈阴道液可与月经周期中可能的排卵期和非排卵期进行定量关联。使用一种新开发的女性可自行操作的容积式阴道抽吸器，可以每天采集宫颈阴道液样本，并记录样本体积或样本重量。在来自7名不同受试者的总共18个周期中，在基础体温（BBT）在月经周期中期发生变化之前，样本体积或样本重量比卵泡早期水平有显著的3至30倍的增加。月经周期中期附近的样本体积或样本重量最大值被定义为“体积峰值”或“重量峰值”。体积峰值或重量峰值的大小在个体受试者中有所不同，介于400至1500微升或毫克之间。体积峰值或重量峰值通常发生在推定排卵前1至2天或当天。随着BBT转变为黄体期水平，样本体积或样本重量急剧下降至卵泡早期水平。结果表明，使用可自行操作的容积式阴道抽吸器测量的宫颈阴道液样本体积或样本重量的变化，可作为自然计划生育方法和评估受孕最佳条件的客观依据。
