Deardorff T L, Kliks M M, Desowitz R S
J Parasitol. 1983 Feb;69(1):191-5.
Terranova Type Hawaii A larvae, gavaged into the stomach of Wistar rats, demonstrated the ability to invade the stomach and intestinal tissues of the rat without penetrating the serosa. Lesions induced by these third-stage larvae were present in 25 of 37 (68%) inoculated rats. Larvae adhered to the mucosa of the stomach within 1 hr PI. Mucosal ulceration and acute, focal, hemorrhagic areas in the mucosa and submucosa were associated with most worm-penetrations. Reactions of inflammatory tissue occurred from 4 hr to 6 days PI and granulomas occurred by day 7 PI. Indurated craterlike lesions were noted 10 to 15 days PI. Resolving granulomas were present by day 30 PI. Chronic gastric ulcers were observed at day 30 PI.
将夏威夷A型泰拉诺瓦幼虫经口灌喂到Wistar大鼠胃内后，其表现出能够侵入大鼠的胃和肠道组织，且不会穿透浆膜。在37只接种的大鼠中，有25只（68%）出现了由这些三期幼虫诱发的损伤。接种后1小时内，幼虫附着于胃黏膜。大多数幼虫穿透处都伴有黏膜溃疡以及黏膜和黏膜下层的急性、局灶性出血区域。接种后4小时至6天出现炎症组织反应，接种后第7天出现肉芽肿。接种后10至15天可见硬结性火山口样损伤。接种后第30天可见正在消退的肉芽肿。接种后第30天观察到慢性胃溃疡。
