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Effect of estrogen treatment on calcium uptake by the rat uterine smooth muscle.

作者信息

Batra S, Sjögren C

出版信息

Life Sci. 1983 Jan 24;32(4):315-9. doi: 10.1016/0024-3205(83)90076-0.

DOI:10.1016/0024-3205(83)90076-0
PMID:6827896
Abstract

The effect of estrogenization on cellular 45Ca uptake by the isolated uterine strips was studied. Whereas estrogenization 1 h before sacrifice of ovariectomized rats caused no significant change in Ca uptake by the isolated uteri, exposure to estrogen 24 h before sacrifice resulted in a significant increase in uptake. Following continuous exposure for 72 h to estrogen, the uptake of Ca was increasd by more than two-fold. Increased Ca uptake following estrogenization may largely account for the increased contractile responses of the uterine smooth muscle particularly those induced by potassium depolarization.

摘要

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