Raju R N, Kardinal C G
South Med J. 1983 Mar;76(3):397-8. doi: 10.1097/00007611-198303000-00030.
Because the liver is the dominant site of lactate clearance and utilization, extensive liver metastases may predispose the patient to the development of lactic acidosis. We have described two patients with hepatic metastatic disease who had fatal lactic acidosis. Greater awareness and prompt treatment of this frequently fatal complication may improve survival of patients with potentially treatable advanced malignancies.
由于肝脏是乳酸清除和利用的主要部位，广泛的肝转移可能使患者易发生乳酸性酸中毒。我们描述了两名患有肝转移性疾病并发生致命性乳酸性酸中毒的患者。提高对这种常见致命并发症的认识并及时治疗，可能会改善患有潜在可治疗的晚期恶性肿瘤患者的生存率。
