肠道钙结合蛋白促进钙的扩散。
Facilitated calcium diffusion by intestinal calcium-binding protein.
作者信息
Feher J J
出版信息
Am J Physiol. 1983 Mar;244(3):C303-7. doi: 10.1152/ajpcell.1983.244.3.C303.
Abstract
The calcium flux through an aqueous compartment was determined using a flow-through dialysis cell in which two dialysis membranes isolated the aqueous compartment. Addition of the intestinal vitamin D-dependent calcium-binding protein (CaBP) significantly enhanced the calcium flux at near physiological calcium concentrations (1 X 10(-6) M). Bovine serum albumin had no effect on the calcium flux. CaBP appears to be one of a class of low molecular weight, soluble binding proteins that enhance ligand diffusion.
摘要
通过使用流通式透析池来测定穿过水相隔室的钙通量，在该透析池中，两个透析膜将水相隔室隔开。添加肠道维生素D依赖性钙结合蛋白（CaBP）在接近生理钙浓度（1×10⁻⁶ M）时显著增强了钙通量。牛血清白蛋白对钙通量没有影响。CaBP似乎是一类增强配体扩散的低分子量可溶性结合蛋白之一。
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