Sepulveda M J, Vallyathan V, Attfield M D, Piacitelli L, Tucker J H
Am Rev Respir Dis. 1983 Feb;127(2):231-5. doi: 10.1164/arrd.1983.127.2.231.
In June 1981, 65 current and former workers at a kaolin mine and mill were examined by chest radiography, spirometry, and a questionnaire. Five (13%) of 39 current workers and 3 (19%) of 16 former workers with 5 yr or more of exposure had radiographic evidence of pneumoconiosis. Among the 8 workers with pneumoconiosis, conglomerate upper lobe lesions were present in one half. No pneumoconiosis was observed among 8 current workers with less than 5 yr of exposure. Lung function testing showed significant reductions (p less than 0.05) in FVC, FEV1, and peak flow rate in kaolin workers compared with that in a control group. Environmental sampling during the testing period showed airborne dust to be composed of kaolinite (96%) and titanium dioxide (4%). Additional controlled epidemiologic studies among kaolin workers are needed to generate reliable prevalence data for pneumoconiosis and to assess the impact of dust exposure on pulmonary function.
1981年6月,对一家高岭土矿和加工厂的65名在职和离职工人进行了胸部X光检查、肺活量测定和问卷调查。39名在职工人中有5名(13%)、16名工作5年及以上的离职工人中有3名(19%)有尘肺病的影像学证据。在8名患有尘肺病的工人中,一半有上叶结节性病变。8名工作年限不足5年的在职工人中未观察到尘肺病。肺功能测试显示,与对照组相比,高岭土工人的用力肺活量(FVC)、第一秒用力呼气容积(FEV1)和峰值流速显著降低(p<0.05)。测试期间的环境采样显示,空气中的粉尘由高岭石(96%)和二氧化钛(4%)组成。需要对高岭土工人进行更多对照流行病学研究,以得出可靠的尘肺病患病率数据,并评估粉尘暴露对肺功能的影响。