Wyler A R, Bolender N F
Ann Neurol. 1983 Jan;13(1):59-64. doi: 10.1002/ana.410130113.
A computerized tomographic (CT) scanning technique has been devised by which the anatomy of the mesial temporal lobe can be examined in epileptics who are being considered for temporal lobectomy. Among 25 patients examined with this technique, 17 have had the anatomy of their mesial temporal lobe verified at craniotomy, showing close correlation between surgical findings and the high-resolution cerebrospinal fluid-enhanced CT scans. Atrophy was present in 4 patients, whereas chronic herniation of the mesial temporal structures over the free edge of the tentorium was present in 12; in 1 patient the structures were normal. The correlation of an anatomical lesion with an electroencephalographically (EEG) defined epileptogenic focus will improve the outcome of surgery for epilepsy. This CT technique aids in identifying the epileptogenic temporal lobe for patients in whom the focus is ambiguous by EEG criteria alone.
已设计出一种计算机断层扫描（CT）技术，通过该技术可对考虑进行颞叶切除术的癫痫患者的内侧颞叶解剖结构进行检查。在使用该技术检查的25例患者中，17例患者的内侧颞叶解剖结构在开颅手术中得到证实，显示手术结果与高分辨率脑脊液增强CT扫描之间存在密切相关性。4例患者存在萎缩，而12例患者存在内侧颞叶结构经小脑幕游离缘的慢性疝；1例患者的结构正常。解剖学病变与脑电图（EEG）定义的致痫灶之间的相关性将改善癫痫手术的结果。对于仅根据EEG标准致痫灶不明确的患者，这种CT技术有助于识别致痫颞叶。
