Poliak M S, Miasnikova L G, Fateeva L I, Ryboshlykov A G, Bychkova G G
Antibiotiki. 1983 Jan;28(1):18-22.
The results of studying aerobic and anaerobic intestinal microflora of rabbits with experimental enterocolitis caused by administration of 7-chlor-7-desoxylincomycin are presented. An increased number of E. coli and some other gram-negative bacteria was noted. It was shown that the quantitative and qualitative composition of the obligate anaerobic microflora was changed: the number of cells of the bacteroids, bifidobacteria, peptococci and peptostreptococci resistant to the antibiotic was low, but the number of clostridia cells resistant to the antibiotic was high. On the basis of a thorough investigation the latter cultures were classified as belonging to Cl. butyricum.
本文展示了对因给予7-氯-7-去氧林可霉素而导致实验性小肠结肠炎的兔子的需氧和厌氧肠道微生物群的研究结果。观察到大肠杆菌和其他一些革兰氏阴性菌数量增加。结果表明,专性厌氧微生物群的数量和质量组成发生了变化:对该抗生素耐药的拟杆菌、双歧杆菌、消化球菌和消化链球菌的细胞数量较少,但对该抗生素耐药的梭菌细胞数量较多。在深入研究的基础上,将后一类培养物归类为丁酸梭菌。