Lisochkin B G, Fateeva L I
Antibiotiki. 1980 Jan;25(1):35-41.
It was found that lincomycin and 7-chlor-7-desoxylincomycin administered 3 times induced severe enterocolitis accompanied by dysbacteriosis in a part of the experimental rabbits, while no such phenomenon was observed in the mice. Treatment of the animals with neomycin for 10 days protected them from death of severe forms of enterocolitis.
结果发现,对部分实验兔三次给予林可霉素和7-氯-7-去氧林可霉素会引发严重的小肠结肠炎并伴有菌群失调,而小鼠未观察到此类现象。用新霉素对动物治疗10天可保护它们免于严重形式的小肠结肠炎致死。