Mattingly W T, O'Connor W, Zeok J V, Todd E P
Ann Thorac Surg. 1983 Mar;35(3):253-6. doi: 10.1016/s0003-4975(10)61553-6.
Thrombosis of the Björk-Shiley prosthesis has been a recognized problem for many years. Review of 172 patients at the University of Kentucky Medical Center who had one or more Björk-Shiley valves inserted between January, 1975, and July, 1980, revealed special problems in those patients with multiple prostheses. Diagnosis and therapy prove more difficult, and the cumulative incidence of thrombosis in the patients with multiple prostheses is 26.8% at six years. Projected long-term use of multiple Björk-Shiley prostheses is discouraged.
多年来， Björk-Shiley人工心脏瓣膜血栓形成一直是个公认的问题。对1975年1月至1980年7月间在肯塔基大学医学中心植入一个或多个Björk-Shiley瓣膜的172例患者进行回顾，发现多瓣膜患者存在特殊问题。诊断和治疗难度更大，多瓣膜患者血栓形成的累积发生率在6年时为26.8%。不建议长期使用多个Björk-Shiley人工心脏瓣膜。
