Soong H K, Quigley H A
Arch Ophthalmol. 1983 Mar;101(3):385-7. doi: 10.1001/archopht.1983.01040010385006.
Dellen may occur in the corneas of eyes with filtering blebs. Nine cases of such dellen were encountered in a series of 97 consecutive trabeculectomies. In two such patients, the dell progressed to a deep corneal ulcer, although in most cases it healed uneventfully with minor changes in therapy. The use of topical prednisolone acetate during the postoperative period may also contribute to dellen formation by inhibiting corneal epithelial wound healing. However, the most important factor predisposing to dellen formation was poor tear-film integrity adjacent to the bleb. The secretion of the aqueous tears seemed to have little or no effect on dellen formation. Almost all dellen occurred in eyes with large filtering blebs.
滤过泡相关的眼的角膜可能会出现角膜凹陷。在连续97例小梁切除术中遇到9例此类角膜凹陷。在其中2例患者中，角膜凹陷进展为深层角膜溃疡，不过在大多数情况下，通过对治疗方案进行微小调整后，角膜凹陷都顺利愈合。术后使用局部醋酸泼尼松龙也可能通过抑制角膜上皮伤口愈合而促使角膜凹陷形成。然而，导致角膜凹陷形成的最重要因素是滤过泡附近泪膜完整性差。房水泪液的分泌似乎对角膜凹陷形成影响很小或没有影响。几乎所有角膜凹陷都出现在有大滤过泡的眼中。
