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[Influence of erythrocyte destruction kinetics on the dynamic behavior of the erythropoiesis system].

作者信息

Flerov M N, Dibrov B F

出版信息

Biofizika. 1983 Jan-Feb;28(1):103-7.

PMID:6830880
Abstract

A simple mathematical model was used to analyse the influence of cell destruction kinetics on the dynamics of erythropoietic system. Two ways of erythrocyte destruction were compared: random destruction and destruction of cells at their maximum age. It has been shown that mostly used description of erythrocyte destruction as a random process results in a great stability increase (about three times in the critical feedback coefficient). Oscillations with large periods (20 divided by 200 days) may exist in the system.

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