Morishita Y
Cancer Lett. 1983 Mar;18(2):229-34. doi: 10.1016/0304-3835(83)90072-1.
Smoke condensates obtained by pyrolysis of the cells of microorganisms isolated from food and cigarettes and of laboratory cultures were shown to be mutagenic to Salmonella typhimurium TA98 and TA100 in incorporation with liver microsomal fraction S-9 mix. The smoke condensates from salt-tolerant bacteria, which belonged to Micrococcus, Bacillus and Corynebacterium spp., showed higher mutagenic activity than those from other less salt-tolerant organisms, fish flesh or pork. Smoke deriving from microorganisms, especially salt-tolerant ones, in food or cigarettes as well as from food components might take part in human carcinogenesis because of the correlation between mutagenicity and carcinogenicity.
从食品、香烟中分离出的微生物细胞以及实验室培养物经热解得到的烟雾浓缩物，与肝微粒体组分S-9混合液一起时，对鼠伤寒沙门氏菌TA98和TA100具有致突变性。来自耐盐细菌（属于微球菌属、芽孢杆菌属和棒状杆菌属）的烟雾浓缩物，其致突变活性高于来自其他耐盐性较低的生物、鱼肉或猪肉的烟雾浓缩物。由于致突变性和致癌性之间的相关性，食品或香烟中的微生物，尤其是耐盐微生物以及食品成分产生的烟雾可能参与人类致癌过程。
